FED INTEREST RATE HIKE coming very soon

The Federal Reserve INTEREST RATE hike is inevitable 

RULE OF THUMB:

When the rates go up the bonds go down.  

How about in a COMPUTER DRIVEN MANIPULATED ALGORITHMIC MARKET?  Is there a RULE OF THUMB THERE or are there ANOTHER SET OF RULES?

http://www.post-gazette.com/business/money/2015/07/10/Investors-prepare-for-inevitable-interest-rate-increase-by-Federal-Reserve/stories/201507100108 

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